IGLCOR22-2

Across TCGA patient cohorts, IGLCOR22-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,157 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLCOR22-2-associated GO terms across cancer lineages are B cell receptor signaling pathway, B cell mediated immunity, and Lymphocyte activation involved in immune response. Each is linked with IGLCOR22-2 in more than 13 cancer types. Because this analysis shows association rather than direction, both IGLCOR22-2-to-partner and partner-to-IGLCOR22-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell receptor signaling pathway grouped by IGLCOR22-2-low versus IGLCOR22-2-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLCOR22-2→partner) and Y-score (partner→IGLCOR22-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell receptor signaling pathway →	+0.080	+0.054	<.001	<.001	3	14
THCA	B cell mediated immunity →	+0.115	+0.055	<.001	<.001	3	14
ESCA	Lymphocyte activation involved in immune response →	+0.054	+0.107	<.001	<.001	3	14
THCA	Immunoglobulin production →	+0.087	+0.058	<.001	<.001	3	14
ESCA	T cell homeostasis →	+0.056	+0.164	<.001	<.001	3	14
THCA	T cell migration →	+0.070	+0.053	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,157 associations by consensus.

B cell receptor signaling pathway by IGLCOR22-2 expression — THCA

Explore this box plot interactively →