IGLCOR22-2

Across TCGA pan-cancer cohorts, IGLCOR22-2 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated IGLCOR22-2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher IGLCOR22-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGLCOR22-2 expression acts as an unfavorable survival marker, although some lineages such as ESCA and HNSC show a favorable association.

ACC, ESCA, and HNSC are the cancer types where IGLCOR22-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	All	0.120	0.728	<.001	39	view →
ESCA	DFS	Tertile	II,III,IV	0.457	0.233	.011	36	view →
HNSC	OS	Tertile	IV	0.865	0.685	.010	30	view →
UCEC	OS	Tertile	All	0.856	0.936	.001	30	view →
READ	OS	Tertile	All	0.637	0.917	.010	30	view →
THYM	DFS	Tertile	All	0.717	0.931	.008	21	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
OV	DFS	Tertile	IV	0.265	0.504	.005	18	view →
COAD	OS	Tertile	IV	0.056	0.659	.002	18	view →
SKCM	OS	Tertile	IV	0.179	0.727	<.001	18	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →
KIRC	DFS	Tertile	All	0.401	0.650	.019	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

IGLCOR22-2–ACC (OS)

Open the ACC breakdown →