Across TCGA patient cohorts, IGLC3 protein abundance is significantly associated with the RNA expression of many other genes, with 975 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLC3-associated genes across cancer lineages are CYB5R3, CTSG, and VCPKMT. Each is linked with IGLC3 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLC3-to-partner and partner-to-IGLC3 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLC3→partner) and Y-score (partner→IGLC3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CYB5R3 →	+0.507	+0.889	.001	<.001	3	1
BRCA	CTSG →	+1.489	+0.716	<.001	.007	3	1
BRCA	VCPKMT →	+0.667	+0.822	.008	.004	3	1
BRCA	ZFYVE21 →	+0.573	+0.773	.005	.003	3	1
BRCA	MYL9 →	+1.053	+0.860	<.001	<.001	3	1
BRCA	RNF125 →	+0.573	+0.808	.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 975 associations by consensus.

Exploration

IGLC3 survival (RNA) · tumor vs normal (RNA) · all IGLC3 data types