IGKV3D-11

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV3D-11 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,360 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV3D-11-associated proteins across cancer lineages are ARHGAP45, SEPTIN1, and DOCK2. Each is linked with IGKV3D-11 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV3D-11-to-partner and partner-to-IGKV3D-11 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV3D-11→partner) and Y-score (partner→IGKV3D-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVARHGAP45 →+0.481+1.877.001<.001310
BRCASEPTIN1 →+0.865+2.328<.001<.001310
GBMDOCK2 →+0.554+0.296<.001<.001310
UCECHCLS1 →+0.739+1.879<.001<.001310
OVIL16 →+0.602+2.073<.001<.001310
OVMZB1 →+1.590+2.453<.001<.001310
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,360 associations by consensus.

Exploration