IGKV2OR2-7D

Across TCGA patient cohorts, IGKV2OR2-7D RNA expression is significantly associated with the go_rna of many other GO terms, with 5,613 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV2OR2-7D-associated GO terms across cancer lineages are Immunoglobulin production, B cell mediated immunity, and Antibacterial humoral response. Each is linked with IGKV2OR2-7D in more than 23 cancer types. Because this analysis shows association rather than direction, both IGKV2OR2-7D-to-partner and partner-to-IGKV2OR2-7D results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin production grouped by IGKV2OR2-7D-low versus IGKV2OR2-7D-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2OR2-7D→partner) and Y-score (partner→IGKV2OR2-7D) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Immunoglobulin production →	+0.079	+0.128	<.001	<.001	3	24
THCA	B cell mediated immunity →	+0.107	+0.245	<.001	<.001	3	23
SARC	Antibacterial humoral response →	+0.183	+0.057	<.001	<.001	3	22
SARC	Antigen receptor-mediated signaling pathway →	+0.066	+0.059	<.001	<.001	3	21
SARC	B cell receptor signaling pathway →	+0.089	+0.052	<.001	<.001	3	21
SARC	Antimicrobial humoral response →	+0.129	+0.056	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,613 associations by consensus.

Immunoglobulin production by IGKV2OR2-7D expression — STAD

Explore this box plot interactively →