IGKV2OR2-7

Across TCGA patient cohorts, IGKV2OR2-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,832 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV2OR2-7-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Antibacterial humoral response. Each is linked with IGKV2OR2-7 in more than 22 cancer types. Because this analysis shows association rather than direction, both IGKV2OR2-7-to-partner and partner-to-IGKV2OR2-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGKV2OR2-7-low versus IGKV2OR2-7-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2OR2-7→partner) and Y-score (partner→IGKV2OR2-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.104	+0.215	<.001	<.001	3	23
THCA	Immunoglobulin production →	+0.074	+0.212	<.001	<.001	3	21
THCA	Antibacterial humoral response →	+0.160	+0.202	<.001	<.001	3	19
SKCM	B cell receptor signaling pathway →	+0.079	+0.119	<.001	<.001	3	19
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.141	+0.184	<.001	<.001	3	18
TGCT	Antigen receptor-mediated signaling pathway →	+0.064	+0.126	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,832 associations by consensus.

B cell mediated immunity by IGKV2OR2-7 expression — THCA

Explore this box plot interactively →