IGKV2OR2-7

Across TCGA pan-cancer cohorts, IGKV2OR2-7 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated IGKV2OR2-7 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher IGKV2OR2-7 RNA is associated with better overall survival. In most high-consensus cancer types, elevated IGKV2OR2-7 expression acts as an unfavorable survival marker, although some lineages such as HNSC and CESC show a favorable association.

HNSC, CESC, and LGG are the cancer types where IGKV2OR2-7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Tertile	III,IV	0.836	0.613	.001	57	view →
CESC	OS	Tertile	All	0.903	0.768	.017	24	view →
LGG	OS	Tertile	All	0.238	0.799	<.001	21	view →
READ	DFS	Tertile	III,IV	0.280	0.762	.002	18	view →
DLBC	OS	Tertile	II,III,IV	0.323	0.920	.026	15	view →
KIRC	OS	Tertile	All	0.529	0.677	.024	12	view →
THCA	OS	Tertile	IV	0.751	1.000	.014	9	view →
LIHC	DFS	Tertile	II,III,IV	0.020	0.414	<.001	9	view →
LUAD	DFS	Quartile	II,III,IV	0.757	0.518	.015	8	view →
BRCA	DFS	Tertile	III,IV	0.888	0.772	.043	6	view →
TGCT	DFS	Tertile	All	1.000	0.804	.022	6	view →
PAAD	OS	Quartile	II,III,IV	0.705	0.489	.036	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

IGKV2OR2-7–HNSC (OS)

Open the HNSC breakdown →