IGKV2D-28

Across TCGA patient cohorts, IGKV2D-28 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,848 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV2D-28-associated proteins across cancer lineages are IL16, CD38, and HCLS1. Each is linked with IGKV2D-28 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV2D-28-to-partner and partner-to-IGKV2D-28 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV2D-28 versus IL16 in UCEC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-28→partner) and Y-score (partner→IGKV2D-28) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IL16 →	+0.597	+1.736	<.001	<.001	3	10
BRCA	CD38 →	+0.994	+1.892	<.001	<.001	3	9
GBM	HCLS1 →	+0.511	+0.207	.002	.003	3	9
OV	MZB1 →	+1.477	+3.200	<.001	<.001	3	9
BRCA	ISG20 →	+0.662	+1.778	<.001	<.001	3	8
UCEC	DEF6 →	+0.455	+1.589	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,848 associations by consensus.

IGKV2D-28 vs IL16 — UCEC

Explore this scatter interactively →