Across TCGA patient cohorts, IGKV2D-26 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,512 significant associations in total. THCA shows the largest number of these associations.

The most reproducible IGKV2D-26-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Antibacterial humoral response. Each is linked with IGKV2D-26 in more than 25 cancer types. Because this analysis shows association rather than direction, both IGKV2D-26-to-partner and partner-to-IGKV2D-26 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-26→partner) and Y-score (partner→IGKV2D-26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.104	+0.275	<.001	<.001	3	25
CHOL	Immunoglobulin production →	+0.086	+0.357	<.001	.008	1	26
THCA	Antibacterial humoral response →	+0.164	+0.263	<.001	<.001	3	22
SKCM	B cell receptor signaling pathway →	+0.097	+0.339	<.001	<.001	3	22
SKCM	B cell activation →	+0.058	+0.317	<.001	<.001	3	21
SKCM	Positive T cell selection →	+0.074	+0.287	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,512 associations by consensus.

Exploration

IGKV2D-26 survival (RNA) · tumor vs normal (RNA) · all IGKV2D-26 data types