IGKV2D-24

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV2D-24 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LIHC shows the largest number of these associations.

The most reproducible IGKV2D-24-associated genes across cancer lineages are GMP. Each is linked with IGKV2D-24 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGKV2D-24-to-partner and partner-to-IGKV2D-24 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GMP grouped by IGKV2D-24-low versus IGKV2D-24-high in LIHC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV2D-24→partner) and Y-score (partner→IGKV2D-24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LIHCGMP →+0.066+3.758.007.04432
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

GMP by IGKV2D-24 expression — LIHC

Box plot of GMP in IGKV2D-24-low vs IGKV2D-24-high samples in LIHC.

Explore this box plot interactively →

Exploration