IGKV1OR2-11

Across TCGA patient cohorts, IGKV1OR2-11 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,927 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGKV1OR2-11-associated GO terms across cancer lineages are B cell mediated immunity, Positive regulation of respiratory burst, and Antimicrobial humoral response. Each is linked with IGKV1OR2-11 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGKV1OR2-11-to-partner and partner-to-IGKV1OR2-11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGKV1OR2-11-low versus IGKV1OR2-11-high in CHOL.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR2-11→partner) and Y-score (partner→IGKV1OR2-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	B cell mediated immunity →	+0.106	+1.003	<.001	.002	3	28
CHOL	Positive regulation of respiratory burst →	+0.175	+0.585	<.001	<.001	3	27
SARC	Antimicrobial humoral response →	+0.109	+0.249	<.001	<.001	3	27
THCA	Antibacterial humoral response →	+0.171	+1.068	<.001	<.001	3	27
CHOL	T cell activation involved in immune response →	+0.055	+0.944	<.001	.006	3	27
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.158	+1.004	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,927 associations by consensus.

B cell mediated immunity by IGKV1OR2-11 expression — CHOL

Explore this box plot interactively →