IGKV1OR-3

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV1OR-3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,508 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGKV1OR-3-associated GO terms across cancer lineages are B cell mediated immunity, Immunoglobulin production, and Regulation of leukocyte proliferation. Each is linked with IGKV1OR-3 in more than 24 cancer types. Because this analysis shows association rather than direction, both IGKV1OR-3-to-partner and partner-to-IGKV1OR-3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1OR-3→partner) and Y-score (partner→IGKV1OR-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
THCAB cell mediated immunity →+0.101+0.492<.001<.001325
STADImmunoglobulin production →+0.069+0.560<.001<.001325
SKCMRegulation of leukocyte proliferation →+0.048+0.224<.001<.001324
SKCMPositive regulation of leukocyte proliferation →+0.053+0.240<.001<.001324
SKCMAntigen receptor-mediated signaling pathway →+0.059+0.237<.001<.001324
SKCMRegulation of tolerance induction →+0.070+0.211<.001<.001324
Each partner links to its Q-omics profile. Showing the 6 strongest of 6,508 associations by consensus.

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