IGKV1D-16

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGKV1D-16 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,686 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGKV1D-16-associated proteins across cancer lineages are CD48, DOCK2, and HCLS1. Each is linked with IGKV1D-16 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGKV1D-16-to-partner and partner-to-IGKV1D-16 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGKV1D-16 versus CD48 in OV, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGKV1D-16→partner) and Y-score (partner→IGKV1D-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVCD48 →+1.073+2.394<.001<.001310
GBMDOCK2 →+0.610+0.463<.001<.001310
UCECHCLS1 →+0.618+1.582<.001<.001310
OVMZB1 →+1.553+2.714<.001<.001310
OVSTK4 →+0.364+1.772.002.00139
GBMWAS →+0.595+0.455<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,686 associations by consensus.

IGKV1D-16 vs CD48 — OV

Per-sample scatter of IGKV1D-16 vs CD48 in OV (Pearson r = 0.37).

Explore this scatter interactively →

Exploration