IGKV1D-13

Across TCGA pan-cancer cohorts, IGKV1D-13 Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated IGKV1D-13 data layer compared with 18 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher IGKV1D-13 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGKV1D-13 expression acts as an unfavorable survival marker.

DLBC are the cancer types where IGKV1D-13 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Median	II,III,IV	0.022	0.837	<.001	12	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

IGKV1D-13–DLBC (DFS)

Open the DLBC breakdown →