IGIP

Across TCGA cell cohorts, IGIP mutation is significantly associated with the mutation status of many other genes, with 251 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IGIP-associated genes across cancer lineages are H1-7, TOPORS, and RASSF4. Each is linked with IGIP in more than 1 cancer types. Because this analysis shows association rather than direction, both IGIP-to-partner and partner-to-IGIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, H1-7 grouped by IGIP-low versus IGIP-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGIP→partner) and Y-score (partner→IGIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	H1-7 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	TOPORS →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	RASSF4 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	CCSER2 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	QKI →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	ENPP5 →	+4.014	+4.969	.008	.008	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 251 associations by consensus.

H1-7 by IGIP expression — BLOOD_Lymphoma

Explore this box plot interactively →