IGHVII-74-1

Across TCGA patient cohorts, IGHVII-74-1 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,521 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHVII-74-1-associated proteins across cancer lineages are FANCI, HAUS6, and RRP1B_S732. Each is linked with IGHVII-74-1 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGHVII-74-1-to-partner and partner-to-IGHVII-74-1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHVII-74-1 versus FANCI in GBM, with a Pearson correlation of -0.31.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-74-1→partner) and Y-score (partner→IGHVII-74-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	FANCI →	-0.580	-0.198	.004	.008	3	3
PDAC	HAUS6 →	-0.388	-0.410	.003	.001	3	3
UCEC	RRP1B_S732 →	-0.502	-0.476	.005	.007	3	3
LUAD	ILF3_S382 →	-1.146	-0.492	.003	.004	3	3
PDAC	KIAA0408 →	+0.650	+0.337	<.001	.001	3	3
PDAC	LHPP →	+0.437	+0.350	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,521 associations by consensus.

IGHVII-74-1 vs FANCI — GBM

Explore this scatter interactively →