IGHVII-74-1

Across TCGA patient cohorts, IGHVII-74-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,356 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVII-74-1-associated GO terms across cancer lineages are Regulation of immunoglobulin production, Mitochondrial transport, and Protein stabilization. Each is linked with IGHVII-74-1 in more than 10 cancer types. Because this analysis shows association rather than direction, both IGHVII-74-1-to-partner and partner-to-IGHVII-74-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of immunoglobulin production grouped by IGHVII-74-1-low versus IGHVII-74-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-74-1→partner) and Y-score (partner→IGHVII-74-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of immunoglobulin production →	+0.068	+0.281	<.001	<.001	3	11
STAD	Mitochondrial transport →	+0.081	+0.197	<.001	<.001	3	9
STAD	Protein stabilization →	+0.081	+0.201	<.001	<.001	3	9
STAD	TORC1 signaling →	+0.090	+0.216	<.001	<.001	3	9
STAD	Response to interleukin-7 →	+0.095	+0.194	<.001	<.001	3	9
STAD	Regulation of cell projection assembly →	+0.074	+0.231	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,356 associations by consensus.

Regulation of immunoglobulin production by IGHVII-74-1 expression — STAD

Explore this box plot interactively →