IGHVII-62-1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHVII-62-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,108 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGHVII-62-1-associated GO terms across cancer lineages are T cell apoptotic process, Positive regulation of stress-activated protein kinase signaling cascade, and JNK cascade. Each is linked with IGHVII-62-1 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGHVII-62-1-to-partner and partner-to-IGHVII-62-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, T cell apoptotic process grouped by IGHVII-62-1-low versus IGHVII-62-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-62-1→partner) and Y-score (partner→IGHVII-62-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADT cell apoptotic process →+0.069+0.063<.001.00136
STADPositive regulation of stress-activated protein kinase signaling cascade →+0.062+0.054<.001.00235
STADJNK cascade →+0.063+0.036<.001.00826
STADCalcium-mediated signaling →+0.052+0.042<.001.00235
STADRegulation of leukocyte apoptotic process →+0.076+0.044<.001.00135
STADNegative regulation of leukocyte apoptotic process →+0.088+0.044<.001.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,108 associations by consensus.

T cell apoptotic process by IGHVII-62-1 expression — STAD

Box plot of T cell apoptotic process in IGHVII-62-1-low vs IGHVII-62-1-high samples in STAD.

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