IGHVII-62-1

Across TCGA pan-cancer cohorts, IGHVII-62-1 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated IGHVII-62-1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher IGHVII-62-1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGHVII-62-1 expression acts as an unfavorable survival marker.

CESC, BLCA, and LIHC are the cancer types where IGHVII-62-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Tertile	All	0.472	0.877	<.001	144	view →
BLCA	OS	Tertile	III,IV	0.509	0.655	<.001	63	view →
LIHC	DFS	Tertile	III,IV	0.080	0.338	.003	54	view →
UCEC	DFS	Tertile	All	0.112	0.651	<.001	36	view →
COAD	OS	Tertile	II,III,IV	0.172	0.859	.001	36	view →
LUSC	DFS	Tertile	II,III,IV	0.176	0.606	<.001	33	view →
LGG	DFS	Tertile	All	0.132	0.826	<.001	18	view →
SKCM	DFS	Tertile	IV	0.016	0.454	<.001	18	view →
THCA	OS	Tertile	III,IV	0.598	0.888	.006	15	view →
KIRC	OS	Tertile	All	0.618	0.808	.035	12	view →
KIRP	OS	Tertile	All	0.279	0.710	.036	9	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

IGHVII-62-1–CESC (OS)

Open the CESC breakdown →