IGHVII-33-1

Across TCGA patient cohorts, IGHVII-33-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,901 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGHVII-33-1-associated GO terms across cancer lineages are Positive regulation of B cell activation, Regulation of mRNA catabolic process, and Lymphocyte apoptotic process. Each is linked with IGHVII-33-1 in more than 10 cancer types. Because this analysis shows association rather than direction, both IGHVII-33-1-to-partner and partner-to-IGHVII-33-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of B cell activation grouped by IGHVII-33-1-low versus IGHVII-33-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHVII-33-1→partner) and Y-score (partner→IGHVII-33-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of B cell activation →	+0.053	+0.073	<.001	<.001	3	11
STAD	Regulation of mRNA catabolic process →	+0.035	+0.068	<.001	<.001	3	11
PAAD	Lymphocyte apoptotic process →	+0.070	+0.055	<.001	<.001	3	11
PAAD	T cell apoptotic process →	+0.081	+0.052	<.001	.001	3	11
PAAD	T cell differentiation in thymus →	+0.059	+0.100	<.001	<.001	3	11
ESCA	Regulation of endoplasmic reticulum unfolded protein response →	+0.044	+0.076	.007	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,901 associations by consensus.

Positive regulation of B cell activation by IGHVII-33-1 expression — STAD

Explore this box plot interactively →