IGHVII-33-1

Across TCGA pan-cancer cohorts, IGHVII-33-1 RNA is linked to patient survival in 12 of 34 cancer types, making it the most broadly survival-associated IGHVII-33-1 data layer.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher IGHVII-33-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGHVII-33-1 expression acts as an unfavorable survival marker, although some lineages such as UCS and SKCM show a favorable association.

STAD, UCS, and KIRC are the cancer types where IGHVII-33-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
STAD	DFS	Tertile	III,IV	0.399	0.623	.001	90	view →
UCS	DFS	Tertile	II,III,IV	1.000	0.269	.006	78	view →
KIRC	OS	Tertile	All	0.410	0.645	<.001	60	view →
COAD	OS	Tertile	IV	0.101	0.658	<.001	36	view →
CESC	OS	Tertile	III,IV	0.068	0.756	<.001	36	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
TGCT	DFS	Tertile	II,III,IV	0.526	0.951	.011	18	view →
UVM	OS	Tertile	All	0.315	0.711	.049	9	view →
THYM	DFS	Tertile	III,IV	0.214	1.000	.017	9	view →
LGG	OS	Tertile	All	0.333	0.830	.012	9	view →
PRAD	OS	Tertile	All	0.964	0.995	.029	6	view →
SKCM	DFS	Quartile	All	0.272	0.189	.043	1	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 12 lineages.

IGHVII-33-1–STAD (DFS)

Open the STAD breakdown →