IGHV5-78

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV5-78 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,358 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV5-78-associated proteins across cancer lineages are ADA2, PTPRC, and NFATC2. Each is linked with IGHV5-78 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGHV5-78-to-partner and partner-to-IGHV5-78 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV5-78→partner) and Y-score (partner→IGHV5-78) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCADA2 →+0.516+0.916<.001<.00135
BRCAPTPRC →+0.573+0.749<.001<.00134
GBMNFATC2 →+0.332+0.218<.001.00225
LSCCINPP5D_S243 →+0.567+0.604<.001<.00134
BRCAANKRD44 →+0.416+1.013<.001<.00134
LSCCBLNK →+0.359+0.672<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,358 associations by consensus.

Exploration