IGHV3OR16-9

Across TCGA patient cohorts, IGHV3OR16-9 protein abundance is significantly associated with the RNA expression of many other genes, with 4,104 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV3OR16-9-associated genes across cancer lineages are AHSA1, MRPL27, and AP1M2. Each is linked with IGHV3OR16-9 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-9-to-partner and partner-to-IGHV3OR16-9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-9 versus AHSA1 in LSCC, with a Pearson correlation of -0.35.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-9→partner) and Y-score (partner→IGHV3OR16-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	AHSA1 →	-0.459	-0.372	.001	<.001	3	3
LUAD	MRPL27 →	-0.453	-0.597	<.001	.002	3	3
LUAD	AP1M2 →	-0.789	-0.585	<.001	<.001	3	3
BRCA	NDUFB11 →	-0.617	-0.618	.001	.001	3	3
LUAD	MRPS23 →	-0.457	-0.459	<.001	.003	3	3
LUAD	NOP9 →	-0.450	-0.494	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,104 associations by consensus.

IGHV3OR16-9 vs AHSA1 — LSCC

Explore this scatter interactively →