IGHV3OR16-13

Across TCGA patient cohorts, IGHV3OR16-13 protein abundance is significantly associated with the RNA expression of many other genes, with 3,920 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV3OR16-13-associated genes across cancer lineages are IL33, ADNP2, and NRF1. Each is linked with IGHV3OR16-13 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHV3OR16-13-to-partner and partner-to-IGHV3OR16-13 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR16-13 versus IL33 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR16-13→partner) and Y-score (partner→IGHV3OR16-13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	IL33 →	+1.254	+1.048	.001	<.001	3	3
LSCC	ADNP2 →	-0.449	-0.888	<.001	.001	3	2
LSCC	NRF1 →	-0.348	-0.968	.006	.005	3	2
LUAD	ZNF862 →	-0.695	-1.131	<.001	<.001	3	2
LSCC	FUBP3 →	-0.332	-1.043	.007	<.001	3	2
LUAD	PCGF1 →	-0.418	-0.911	.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,920 associations by consensus.

IGHV3OR16-13 vs IL33 — LSCC

Explore this scatter interactively →