IGHV3OR15-7

Across TCGA patient cohorts, IGHV3OR15-7 protein abundance is significantly associated with the RNA expression of many other genes, with 12,378 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHV3OR15-7-associated genes across cancer lineages are PRRX2, FCAR, and IGKV1D-39. Each is linked with IGHV3OR15-7 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGHV3OR15-7-to-partner and partner-to-IGHV3OR15-7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV3OR15-7 versus PRRX2 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3OR15-7→partner) and Y-score (partner→IGHV3OR15-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PRRX2 →	+1.525	+0.706	.002	.001	3	4
GBM	FCAR →	+0.649	+0.574	<.001	<.001	3	4
LSCC	IGKV1D-39 →	+1.648	+0.570	<.001	<.001	3	4
BRCA	LOX →	+1.112	+0.620	<.001	<.001	3	4
BRCA	FN1 →	+1.413	+0.559	<.001	.003	3	4
GBM	CPXM2 →	+1.187	+0.658	.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,378 associations by consensus.

IGHV3OR15-7 vs PRRX2 — UCEC

Explore this scatter interactively →