IGHV3-23

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV3-23 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,170 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHV3-23-associated proteins across cancer lineages are ARHGAP45, MZB1, and DOCK2. Each is linked with IGHV3-23 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHV3-23-to-partner and partner-to-IGHV3-23 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-23→partner) and Y-score (partner→IGHV3-23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMARHGAP45 →+0.622+2.110<.001<.001310
OVMZB1 →+1.597+4.755<.001<.001310
GBMDOCK2 →+0.663+1.988<.001<.001310
GBMHCLS1 →+0.742+1.967<.001<.001310
BRCAIL16 →+0.652+3.185<.001<.001310
GBMWAS →+0.695+2.006<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,170 associations by consensus.

Exploration