Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV3-23 mutation is significantly associated with the RNA expression of many other genes, with 1,408 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGHV3-23-associated genes across cancer lineages are HINT1, MIR4681, and EEF1E1-BLOC1S5. Each is linked with IGHV3-23 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-23-to-partner and partner-to-IGHV3-23 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV3-23→partner) and Y-score (partner→IGHV3-23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.