IGHV3-20

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV3-20 protein abundance is significantly associated with the RNA expression of many other genes, with 4,768 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGHV3-20-associated genes across cancer lineages are BPTF, RN7SL126P, and ALG6. Each is linked with IGHV3-20 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGHV3-20-to-partner and partner-to-IGHV3-20 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-20→partner) and Y-score (partner→IGHV3-20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADBPTF →-0.360-0.436<.001.00633
HNSCRN7SL126P →+0.896+0.632.009.00733
GBMALG6 →-0.477-0.462.002.00833
HNSCVNN2 →+0.778+0.774.007<.00132
GBMYLPM1 →-0.446-0.606<.001<.00132
GBMNUP214 →-0.423-0.576<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,768 associations by consensus.

Exploration