IGHV3-16

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHV3-16 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGHV3-16-associated genes across cancer lineages are ACC_pS79 and JNK2. Each is linked with IGHV3-16 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-16-to-partner and partner-to-IGHV3-16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV3-16→partner) and Y-score (partner→IGHV3-16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECACC_pS79 →+0.491+3.000.014.03721
UCECJNK2 →+0.304+3.000.008.03721
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

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