Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV3-11 mutation is significantly associated with the RNA expression of many other genes, with 31 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGHV3-11-associated genes across cancer lineages are CUL4AP1, CLUHP11, and RNU6-1124P. Each is linked with IGHV3-11 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV3-11-to-partner and partner-to-IGHV3-11 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV3-11→partner) and Y-score (partner→IGHV3-11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.