IGHV1OR16-3

Across TCGA patient cohorts, IGHV1OR16-3 RNA expression is significantly associated with the protein abundance of many other proteins, with 6,159 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHV1OR16-3-associated proteins across cancer lineages are MZB1, CD38, and HCLS1. Each is linked with IGHV1OR16-3 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGHV1OR16-3-to-partner and partner-to-IGHV1OR16-3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHV1OR16-3 versus MZB1 in CCRCC, with a Pearson correlation of 0.65.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR16-3→partner) and Y-score (partner→IGHV1OR16-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	MZB1 →	+1.377	+0.362	<.001	<.001	3	7
CCRCC	CD38 →	+0.930	+0.487	<.001	.001	3	6
UCEC	HCLS1 →	+0.514	+0.413	<.001	.005	3	6
LSCC	IL16 →	+0.477	+1.222	<.001	<.001	3	6
CCRCC	ADA2 →	+0.491	+0.356	<.001	.001	3	5
LSCC	CARMIL2_S1381 →	+0.799	+0.960	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,159 associations by consensus.

IGHV1OR16-3 vs MZB1 — CCRCC

Explore this scatter interactively →