IGHV1OR16-3

Across TCGA patient cohorts, IGHV1OR16-3 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,877 significant associations in total. COAD shows the largest number of these associations.

The most reproducible IGHV1OR16-3-associated GO terms across cancer lineages are B cell mediated immunity, Regulation of B cell activation, and Humoral immune response mediated by circulating immunoglobulin. Each is linked with IGHV1OR16-3 in more than 26 cancer types. Because this analysis shows association rather than direction, both IGHV1OR16-3-to-partner and partner-to-IGHV1OR16-3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGHV1OR16-3-low versus IGHV1OR16-3-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR16-3→partner) and Y-score (partner→IGHV1OR16-3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.100	+0.991	<.001	<.001	3	27
ESCA	Regulation of B cell activation →	+0.063	+0.810	<.001	<.001	3	26
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.156	+0.898	<.001	<.001	3	26
SKCM	Regulation of B cell differentiation →	+0.079	+0.600	<.001	<.001	3	26
STAD	Regulation of lymphocyte differentiation →	+0.046	+0.583	<.001	<.001	3	26
THCA	Antibacterial humoral response →	+0.168	+0.918	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,877 associations by consensus.

B cell mediated immunity by IGHV1OR16-3 expression — THCA

Explore this box plot interactively →