IGHV1OR16-1

Across TCGA patient cohorts, IGHV1OR16-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,831 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHV1OR16-1-associated GO terms across cancer lineages are B cell mediated immunity, Humoral immune response mediated by circulating immunoglobulin, and B cell receptor signaling pathway. Each is linked with IGHV1OR16-1 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGHV1OR16-1-to-partner and partner-to-IGHV1OR16-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGHV1OR16-1-low versus IGHV1OR16-1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR16-1→partner) and Y-score (partner→IGHV1OR16-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	B cell mediated immunity →	+0.096	+1.030	<.001	<.001	3	28
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.160	+0.642	<.001	<.001	3	28
CHOL	B cell receptor signaling pathway →	+0.090	+0.386	<.001	.004	3	27
THCA	Antimicrobial humoral response →	+0.111	+0.655	<.001	<.001	3	27
SKCM	Antigen receptor-mediated signaling pathway →	+0.057	+0.557	<.001	<.001	3	26
PAAD	Dendritic cell apoptotic process →	+0.092	+0.738	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,831 associations by consensus.

B cell mediated immunity by IGHV1OR16-1 expression — ESCA

Explore this box plot interactively →