IGHV1OR15-6

Across TCGA patient cohorts, IGHV1OR15-6 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,737 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGHV1OR15-6-associated GO terms across cancer lineages are Immunoglobulin production, B cell receptor signaling pathway, and B cell mediated immunity. Each is linked with IGHV1OR15-6 in more than 22 cancer types. Because this analysis shows association rather than direction, both IGHV1OR15-6-to-partner and partner-to-IGHV1OR15-6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Immunoglobulin production grouped by IGHV1OR15-6-low versus IGHV1OR15-6-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHV1OR15-6→partner) and Y-score (partner→IGHV1OR15-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Immunoglobulin production →	+0.074	+0.260	<.001	<.001	3	23
THCA	B cell receptor signaling pathway →	+0.067	+0.181	<.001	<.001	3	21
THCA	B cell mediated immunity →	+0.100	+0.212	<.001	<.001	3	21
THCA	Antibacterial humoral response →	+0.153	+0.190	<.001	<.001	3	20
LIHC	B cell differentiation →	+0.044	+0.055	<.001	<.001	3	20
THCA	Antigen receptor-mediated signaling pathway →	+0.050	+0.209	<.001	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,737 associations by consensus.

Immunoglobulin production by IGHV1OR15-6 expression — ESCA

Explore this box plot interactively →