Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGHV1-58 mutation is significantly associated with the RNA expression of many other genes, with 101 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGHV1-58-associated genes across cancer lineages are MIR215, LINC02348, and RNU6-236P. Each is linked with IGHV1-58 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHV1-58-to-partner and partner-to-IGHV1-58 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGHV1-58→partner) and Y-score (partner→IGHV1-58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.