Across TCGA patient cohorts, IGHJ2 RNA expression is significantly associated with the RNA expression of many other genes, with 11,372 significant associations in total. TGCT shows the largest number of these associations.

The most reproducible IGHJ2-associated genes across cancer lineages are IGHV1-18, IGHV3-20, and IGHV3-48. Each is linked with IGHJ2 in more than 32 cancer types. Because this analysis shows association rather than direction, both IGHJ2-to-partner and partner-to-IGHJ2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHJ2→partner) and Y-score (partner→IGHJ2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	IGHV1-18 →	+5.181	+3.640	<.001	<.001	3	33
HNSC	IGHV3-20 →	+2.641	+3.528	<.001	<.001	3	33
THCA	IGHV3-48 →	+3.678	+3.540	<.001	<.001	3	33
THCA	IGHV4-61 →	+3.284	+3.546	<.001	<.001	3	33
THCA	IGHV3-73 →	+3.675	+3.467	<.001	<.001	3	33
HNSC	IGKV1D-16 →	+3.039	+3.647	<.001	<.001	3	33

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,372 associations by consensus.

Exploration

IGHJ2 survival (RNA) · tumor vs normal (RNA) · all IGHJ2 data types