IGHG4

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHG4 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,952 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IGHG4-associated proteins across cancer lineages are MZB1, LSP1, and PTPN7. Each is linked with IGHG4 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGHG4-to-partner and partner-to-IGHG4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHG4→partner) and Y-score (partner→IGHG4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMZB1 →+1.300+3.060<.001<.001310
HNSCLSP1 →+0.651+3.166<.001<.00139
OVPTPN7 →+0.450+1.966<.001<.00138
OVARHGAP45 →+0.515+2.457<.001<.00138
UCECWAS →+0.525+2.904<.001<.00138
OVWIPF1 →+0.458+2.529<.001<.00138
Each partner links to its Q-omics profile. Showing the 6 strongest of 12,952 associations by consensus.

Exploration