IGHEP2

Across TCGA patient cohorts, IGHEP2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,092 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHEP2-associated proteins across cancer lineages are SAMHD1, GBP4, and RASAL3. Each is linked with IGHEP2 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGHEP2-to-partner and partner-to-IGHEP2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGHEP2 versus SAMHD1 in HNSC, with a Pearson correlation of 0.46.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHEP2→partner) and Y-score (partner→IGHEP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	SAMHD1 →	+0.628	+0.685	<.001	<.001	3	7
HNSC	GBP4 →	+0.914	+0.835	<.001	<.001	3	7
HNSC	RASAL3 →	+0.453	+0.844	<.001	<.001	3	6
HNSC	PSMB10 →	+0.587	+0.843	<.001	<.001	3	6
HNSC	WDFY4 →	+0.517	+0.648	<.001	<.001	3	6
GBM	SYK →	+0.425	+0.339	.001	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,092 associations by consensus.

IGHEP2 vs SAMHD1 — HNSC

Explore this scatter interactively →