Across TCGA patient cohorts, IGHD6-19 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,914 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHD6-19-associated proteins across cancer lineages are GIMAP4, GIMAP7, and IL16. Each is linked with IGHD6-19 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGHD6-19-to-partner and partner-to-IGHD6-19 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD6-19→partner) and Y-score (partner→IGHD6-19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	GIMAP4 →	+0.466	+0.950	<.001	.002	3	7
UCEC	GIMAP7 →	+0.500	+0.800	<.001	.001	3	7
BRCA	IL16 →	+0.508	+0.907	<.001	<.001	3	7
UCEC	MYO1F →	+0.518	+0.787	<.001	.001	3	6
UCEC	NCKAP1L →	+0.554	+1.032	<.001	<.001	3	6
UCEC	ARHGAP30 →	+0.509	+0.586	.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,914 associations by consensus.

Exploration

IGHD6-19 survival (RNA) · tumor vs normal (RNA) · all IGHD6-19 data types