Across TCGA patient cohorts, IGHD5-24 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,683 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGHD5-24-associated GO terms across cancer lineages are Mature B cell differentiation involved in immune response, B cell mediated immunity, and Leukocyte apoptotic process. Each is linked with IGHD5-24 in more than 14 cancer types. Because this analysis shows association rather than direction, both IGHD5-24-to-partner and partner-to-IGHD5-24 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD5-24→partner) and Y-score (partner→IGHD5-24) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Mature B cell differentiation involved in immune response →	+0.075	+0.484	<.001	<.001	3	14
THCA	B cell mediated immunity →	+0.127	+0.172	<.001	<.001	3	14
COAD	Leukocyte apoptotic process →	+0.051	+0.240	<.001	<.001	3	13
UCEC	Regulation of B cell proliferation →	+0.086	+0.153	<.001	.008	1	15
STAD	T cell proliferation →	+0.050	+0.338	<.001	<.001	3	13
BLCA	B cell activation →	+0.074	+0.105	<.001	.005	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,683 associations by consensus.

Exploration

IGHD5-24 survival (RNA) · tumor vs normal (RNA) · all IGHD5-24 data types