Across TCGA pan-cancer cohorts, IGHD4OR15-4B RNA is linked to patient survival in 2 of 34 cancer types, making it the most broadly survival-associated IGHD4OR15-4B data layer.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IGHD4OR15-4B RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGHD4OR15-4B expression acts as an unfavorable survival marker.
LUAD and LGG are the cancer types where IGHD4OR15-4B RNA most reproducibly stratifies survival.