Q-omics provides the consensus-scored IGHD4OR15-4B profile across patient tissues and cancer cell-line models. IGHD4OR15-4B expression is associated with patient survival in 2 of 34 cancer types, with the highest sampling consensus in LUAD. Additionally, IGHD4OR15-4B RNA expression shows 7 significant gene co-expression associations, with the highest sampling consensus in LGG. Together, these results highlight LUAD, and LGG as cancer lineages where IGHD4OR15-4B shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGHD4OR15-4B survival associations across molecular data types. IGHD4OR15-4B RNA expression shows survival associations in the most cancer types (2). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGHD4OR15-4B data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	2	LUAD (18)	view →

This table ranks reproducible IGHD4OR15-4B RNA expression–survival associations across cancer types. High IGHD4OR15-4B expression shows unfavorable associations in LUAD and LGG. The LUAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .014). Together, the overview and detailed table identify LUAD as the clearest survival context for IGHD4OR15-4B RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.218	0.676	.014	18	view →
LGG	OS	Tertile	All	0.591	0.908	.041	6	view →

Pink = unfavorable, green = favorable. all 2 lineages →

IGHD4OR15-4B-LUAD (DFS)

Kaplan–Meier survival curve for IGHD4OR15-4B RNA expression in LUAD: high vs low expression groups.

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Cross-omics associations

This table shows molecular features associated with IGHD4OR15-4B in patient tissues and cancer cell lines. In patient samples, IGHD4OR15-4B shows the broadest associations at the RNA and protein expression levels, with LGG recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7	LGG (7)	view →
Infiltrating cells	3	LGG (3)	view →