IGHD1OR15-1B

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHD1OR15-1B RNA expression is significantly associated with the go_rna of many other GO terms, with 205 significant associations in total. LAML shows the largest number of these associations.

The most reproducible IGHD1OR15-1B-associated GO terms across cancer lineages are Microtubule-based protein transport, Regulation of neurotransmitter receptor activity, and Neurotransmitter receptor transport. Each is linked with IGHD1OR15-1B in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHD1OR15-1B-to-partner and partner-to-IGHD1OR15-1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule-based protein transport grouped by IGHD1OR15-1B-low versus IGHD1OR15-1B-high in LAML.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD1OR15-1B→partner) and Y-score (partner→IGHD1OR15-1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LAMLMicrotubule-based protein transport →+0.123+0.443<.001.00131
LAMLRegulation of neurotransmitter receptor activity →+0.088+0.473<.001<.00131
LAMLNeurotransmitter receptor transport →+0.096+0.419<.001.00331
LAMLRegulation of signaling receptor activity →+0.047+0.694<.001<.00131
LAMLDendrite arborization →+0.143+0.450<.001.00131
LAMLRegulation of non-canonical NF-kappaB signal transduction →+0.053+0.488<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 205 associations by consensus.

Microtubule-based protein transport by IGHD1OR15-1B expression — LAML

Box plot of Microtubule-based protein transport in IGHD1OR15-1B-low vs IGHD1OR15-1B-high samples in LAML.

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Exploration