IGHD1OR15-1A

Across TCGA patient cohorts, IGHD1OR15-1A RNA expression is significantly associated with the go_rna of many other GO terms, with 139 significant associations in total. LGG shows the largest number of these associations.

The most reproducible IGHD1OR15-1A-associated GO terms across cancer lineages are Transcription elongation-coupled chromatin remodeling, Regulation of transcription regulatory region DNA binding, and Positive regulation of DNA recombination. Each is linked with IGHD1OR15-1A in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHD1OR15-1A-to-partner and partner-to-IGHD1OR15-1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Transcription elongation-coupled chromatin remodeling grouped by IGHD1OR15-1A-low versus IGHD1OR15-1A-high in LGG.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD1OR15-1A→partner) and Y-score (partner→IGHD1OR15-1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LGG	Transcription elongation-coupled chromatin remodeling →	+0.033	+0.139	.002	.001	3	1
LGG	Regulation of transcription regulatory region DNA binding →	+0.030	+0.122	.003	.001	3	1
LGG	Positive regulation of DNA recombination →	+0.022	+0.103	.007	.001	3	1
LGG	Phosphatidylserine metabolic process →	+0.041	+0.094	<.001	<.001	3	1
LAML	Long-chain fatty acid import across plasma membrane →	+0.086	+0.560	.002	.001	3	1
LAML	Regulation of opsonization →	+0.192	+0.543	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 139 associations by consensus.

Transcription elongation-coupled chromatin remodeling by IGHD1OR15-1A expression — LGG

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