IGHD1OR15-1A

Across TCGA pan-cancer cohorts, IGHD1OR15-1A RNA is linked to patient survival in 3 of 34 cancer types, making it the most broadly survival-associated IGHD1OR15-1A data layer.

The strongest signal is observed in uveal melanoma (UVM), where higher IGHD1OR15-1A RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGHD1OR15-1A expression acts as an unfavorable survival marker.

UVM, STAD, and ESCA are the cancer types where IGHD1OR15-1A RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UVM	OS	Tertile	II,III,IV	0.213	0.718	.002	81	view →
STAD	DFS	Tertile	All	0.146	0.715	<.001	45	view →
ESCA	OS	Tertile	II,III,IV	0.321	0.685	.035	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

IGHD1OR15-1A–UVM (OS)

Open the UVM breakdown →