Across TCGA patient cohorts, IGHD1-26 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,440 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGHD1-26-associated proteins across cancer lineages are EVI2B_S268, P2RY8_S324, and IL16. Each is linked with IGHD1-26 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGHD1-26-to-partner and partner-to-IGHD1-26 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHD1-26→partner) and Y-score (partner→IGHD1-26) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	EVI2B_S268 →	+0.857	+1.317	<.001	<.001	3	5
OV	P2RY8_S324 →	+1.107	+0.658	<.001	.004	3	5
BRCA	IL16 →	+0.721	+0.947	<.001	<.001	3	5
HNSC	SEC11C →	+1.073	+0.972	<.001	<.001	3	5
BRCA	SEPTIN1 →	+1.002	+0.858	<.001	<.001	3	5
LSCC	STK10_S438 →	+0.594	+1.611	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,440 associations by consensus.

Exploration

IGHD1-26 survival (RNA) · tumor vs normal (RNA) · all IGHD1-26 data types