IGHA1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGHA1 mutation is significantly associated with the RNA expression of many other genes, with 477 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGHA1-associated genes across cancer lineages are RNU4-15P, NUDT4P2, and BNIP3P41. Each is linked with IGHA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGHA1-to-partner and partner-to-IGHA1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGHA1→partner) and Y-score (partner→IGHA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU4-15P →+0.244+5.147<.001.00332
BLCANUDT4P2 →+0.083+4.971.001.00232
COADBNIP3P41 →+0.051+6.149<.001<.00132
UCECACO1 →+0.569+3.338.005.00532
BLCARN7SL831P →+0.220+4.363<.001.00732
BLCARNU6ATAC9P →+0.450+4.463<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 477 associations by consensus.

Exploration