Across TCGA patient cohorts, IGFL4 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,133 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGFL4-associated proteins across cancer lineages are SEPTIN11, SEPTIN7, and GSN. Each is linked with IGFL4 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGFL4-to-partner and partner-to-IGFL4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL4→partner) and Y-score (partner→IGFL4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SEPTIN11 →	+0.276	+0.211	<.001	<.001	3	4
PDAC	SEPTIN7 →	+0.309	+0.686	<.001	<.001	3	4
PDAC	GSN →	+0.637	+0.399	<.001	<.001	3	4
COAD	UBA2 →	+0.361	+1.472	<.001	<.001	3	4
GBM	LDLRAP1 →	-0.507	-0.654	.002	<.001	3	4
OV	MRPS10 →	-0.427	-0.636	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,133 associations by consensus.

Exploration

IGFL4 survival (RNA) · tumor vs normal (RNA) · all IGFL4 data types