Across TCGA patient cohorts, IGFL3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,978 significant associations in total. GBM shows the largest number of these associations.

The most reproducible IGFL3-associated proteins across cancer lineages are AEBP1, THBS2, and P3H1. Each is linked with IGFL3 in more than 7 cancer types. Because this analysis shows association rather than direction, both IGFL3-to-partner and partner-to-IGFL3 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL3→partner) and Y-score (partner→IGFL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	AEBP1 →	+1.016	+1.207	<.001	<.001	3	8
OV	THBS2 →	+1.459	+0.542	<.001	<.001	3	7
OV	P3H1 →	+0.609	+0.415	<.001	<.001	3	7
OV	P3H3 →	+0.699	+0.351	<.001	<.001	3	7
BRCA	P4HA2 →	+0.759	+1.132	<.001	<.001	3	7
BRCA	PPFIBP1 →	+0.529	+1.290	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,978 associations by consensus.

Exploration

IGFL3 survival (RNA) · tumor vs normal (RNA) · all IGFL3 data types