Across TCGA patient cohorts, IGFL2 mutation is significantly associated with the RNA expression of many other genes, with 47 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGFL2-associated genes across cancer lineages are RNU6-3P, MIR6078, and RNU1-57P. Each is linked with IGFL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGFL2-to-partner and partner-to-IGFL2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGFL2→partner) and Y-score (partner→IGFL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-3P →	+0.381	+3.255	.001	.005	3	2
LUAD	MIR6078 →	+0.414	+7.930	<.001	.008	3	2
UCEC	RNU1-57P →	+0.276	+4.470	<.001	.004	3	2
UCEC	RNU6-380P →	+0.206	+4.470	<.001	.004	3	2
UCEC	LINC02238 →	+0.078	+3.198	.002	.007	3	2
SKCM	NPAP1P7 →	+0.810	+3.770	.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 47 associations by consensus.

Exploration

IGFL2 survival (RNA) · tumor vs normal (RNA) · all IGFL2 data types